UU
Umeå UniversityPostdoc in MLL1 Leukaemia Research, Umeå University
Fully FundedUmeå, Swedenpostdoctoral· Scholarship stipend for 2 years (amount not specified).
Project Overview
2-year postdoctoral fellowship in molecular mechanisms of MLL1-driven leukaemia at Umeå University. Full-time, starts 1 Jan 2027. Apply by 16 Nov 2026.
Project Description
The Department of Molecular Biology at Umeå University offers a postdoctoral scholarship in Medical Science focusing on molecular mechanisms of MLL1-driven leukaemia. The scholarship is full-time for two years, beginning 1 January 2027 or by agreement. Application deadline is 16 November 2026.
Research Group
The molecular epigenetics lab (Yuri Schwartz) is a dynamic and stimulating multidisciplinary research environment focused on regulatory mechanisms that enable cells to retain their identity. The lab employs Drosophila and human cell culture models, genomics, genetics, and numerical simulations to understand molecular mechanisms of epigenetic regulation by Polycomb and Trithorax group proteins.
Research Focus
Chromosomal rearrangements of the human MLL1 gene are associated with de novo and therapy-induced paediatric and adult acute leukaemia. The project addresses key questions:
- Does MLL1 act by limiting epigenetic repression of developmental genes?
- Do oncogenic fusions perturb epigenetic repression of alternative gene expression programs?
- Is MLL1 methyltransferase activity critical for oncogenic function, and what are the relevant substrates?
The Department of Molecular Biology at Umeå University offers a postdoctoral scholarship in Medical Science focusing on molecular mechanisms of MLL1-driven leukaemia. The scholarship is full-time for two years, beginning 1 January 2027 or by agreement. Application deadline is 16 November 2026.
Research Group
The molecular epigenetics lab (Yuri Schwartz) is a dynamic and stimulating multidisciplinary research environment focused on regulatory mechanisms that enable cells to retain their identity. The lab employs Drosophila and human cell culture models, genomics, genetics, and numerical simulations to understand molecular mechanisms of epigenetic regulation by Polycomb and Trithorax group proteins.
Research Focus
Chromosomal rearrangements of the human MLL1 gene are associated with de novo and therapy-induced paediatric and adult acute leukaemia. The project addresses key questions:
- Does MLL1 act by limiting epigenetic repression of developmental genes?
- Do oncogenic fusions perturb epigenetic repression of alternative gene expression programs?
- Is MLL1 methyltransferase activity critical for oncogenic function, and what are the relevant substrates?
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